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MBL Life science pso2 protein
Pso2 Protein, supplied by MBL Life science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pso2 protein/product/MBL Life science
Average 90 stars, based on 1 article reviews
pso2 protein - by Bioz Stars, 2026-05
90/100 stars

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Tiefenbach GmbH pso2 protein
Function of Hrq1 and <t>Pso2</t> in ICL repair and consequences of their deletion. Following NER-induced incisions on either side of the ICL (red line), Hrq1 (blue) and Pso2 (orange) are recruited to digest one strand of DNA between the incisions. In the absence of Hrq1, Pso2 retains minimal translesional nuclease activity, so some lesions persist. In the absence of Pso2, alternative repair machinery can be recruited to repair the lesion, but most ICLs persist and lead to cell death.
Pso2 Protein, supplied by Tiefenbach GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pso2 protein/product/Tiefenbach GmbH
Average 90 stars, based on 1 article reviews
pso2 protein - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier

90
MBL Life science pso2 protein
Function of Hrq1 and <t>Pso2</t> in ICL repair and consequences of their deletion. Following NER-induced incisions on either side of the ICL (red line), Hrq1 (blue) and Pso2 (orange) are recruited to digest one strand of DNA between the incisions. In the absence of Hrq1, Pso2 retains minimal translesional nuclease activity, so some lesions persist. In the absence of Pso2, alternative repair machinery can be recruited to repair the lesion, but most ICLs persist and lead to cell death.
Pso2 Protein, supplied by MBL Life science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pso2 protein/product/MBL Life science
Average 90 stars, based on 1 article reviews
pso2 protein - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier

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Function of Hrq1 and Pso2 in ICL repair and consequences of their deletion. Following NER-induced incisions on either side of the ICL (red line), Hrq1 (blue) and Pso2 (orange) are recruited to digest one strand of DNA between the incisions. In the absence of Hrq1, Pso2 retains minimal translesional nuclease activity, so some lesions persist. In the absence of Pso2, alternative repair machinery can be recruited to repair the lesion, but most ICLs persist and lead to cell death.

Journal: Progress in biophysics and molecular biology

Article Title: Fanconi anemia-independent DNA inter-strand crosslink repair in eukaryotes

doi: 10.1016/j.pbiomolbio.2020.08.005

Figure Lengend Snippet: Function of Hrq1 and Pso2 in ICL repair and consequences of their deletion. Following NER-induced incisions on either side of the ICL (red line), Hrq1 (blue) and Pso2 (orange) are recruited to digest one strand of DNA between the incisions. In the absence of Hrq1, Pso2 retains minimal translesional nuclease activity, so some lesions persist. In the absence of Pso2, alternative repair machinery can be recruited to repair the lesion, but most ICLs persist and lead to cell death.

Article Snippet: However, previous work with Pso2 did not demonstrate translesion nuclease activity ( Tiefenbach and Junop, 2012 ), suggesting that an accessory factor is required to promote digestion through the lesion.

Techniques: Activity Assay